Immunodeficient Rodents

A Guide to Their Immunobiology, Husbandry, and Use

von Committee on Immunologically Compromised Rodents, National Research Council, Commission On Life Sciences, Institute For Laboratory Animal Research

260 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.