Bioconductor Case Studies

von Florian Hahne, Wolfgang Huber, Robert Gentleman, Seth Falcon

284 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include: (1) import and preprocessing of data from various sources; (2) statistical modeling of differential gene expression; (3) biological metadata; (4) application of graphs and graph rendering; (5) machine learning for clustering and classification problems; (6) gene set enrichment analysis.

Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table.

• Reihe: Use R!
• ISBN: 9780387772394
• Sprache: Englisch
• Erscheinungsdatum: 15.08.2008
• Genre: Biologie
• Verlag: Springer US