Kinase Targets and Drug Discovery

374 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

Kinase Targets and Drug Discovery covers the critical role of kinases as regulators of cellular functions and their implications in a range of diseases, from cancers to cardiovascular disorders and inflammatory conditions. Readers will explore foundational concepts on the functions of kinases, the role of kinase inhibitors in disease therapy, and challenges faced. The second section focuses on innovative strategies in kinase drug discovery, covering screening and computational approaches, along with the development of covalent, macrocyclic, allosteric inhibitors, and kinase degraders. Final sections examine clinical applications, detailing how kinase inhibition can be harnessed for cancer therapies, non-oncologic diseases, and even non-catalytic functions.This book will serve as an indispensable resource for pharmacologists, medicinal chemists, and researchers in both academia and industry. By bridging the gap between foundational research and clinical application, it equips professionals with the latest insights and practical approaches to advance their understanding to contribute meaningfully to the evolving landscape of drug discovery.

• Themen: Medizin Medizinische Spezialgebiete Pharmakologie
• ISBN: 9780443439742
• Sprache: Englisch
• Erscheinungsdatum: 22.04.2026
• Größe: 234 x 190 mm
• Verlag: Elsevier Science
• Herausgegeben von: Xiaoyun Lu