Dynamic Combinatorial Chemistry

In Drug Discovery, Bioorganic Chemistry, and Materials Science

280 Seiten, Hardcover

Kurzbeschreibung des Verlags

Effective techniques for applying Dynamic Combinatorial Chemistry In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Chapters cover: - Basic theory - Approaches to binding in proteins and nucleic acids - Molecular recognition - Self-sorting - Catalyst discovery - Materials discovery - Analytical chemistry challenges A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.

• ISBN: 9780470096031
• Sprache: Englisch
• Erscheinungsdatum: 01.12.2009
• Größe: 236 x 155 mm
• Verlag: Wiley
• Herausgegeben von: Benjamin L Miller