Pharmaco Modeling w/NONMEM

von Fiedler-Kelly, Owen

320 Seiten, Hardcover

Kurzbeschreibung des Verlags

This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. ¿ Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects ¿ Provides examples of nonlinear modeling concepts and estimation basics with discussion on  the model building process and applications of empirical Bayesian estimates in the drug development environment ¿ Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control ¿ Has datasets, programming code, and practice exercises with solutions, available on a supplementary website

• ISBN: 9780470582299
• Sprache: Englisch
• Erscheinungsdatum: 27.06.2014
• Größe: 240 x 161 mm
• Verlag: John Wiley & Sons