The Human Complement System in Health and Disease

668 Seiten, Hardcover

Kurzbeschreibung des Verlags

This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease- describes the molecular architecture of the complement system - details the structure of complement genes - discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins - analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway - elucidates the regulation of complement gene expression and the structure and function of bioactive peptides - explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria - and more!

• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Biowissenschaften, allgemein Genetik (nicht-medizinisch)
• ISBN: 9780824798987
• Sprache: Englisch
• Erscheinungsdatum: 01.02.1998
• Größe: 259 x 182 mm
• Verlag: Taylor & Francis Ltd (Sales)
• Herausgegeben von: John E Volanakis