Protein Evolution

Methods and Protocols

320 Seiten, Hardcover

Kurzbeschreibung des Verlags

This volume details computational tools for the study of protein evolution based on 1D-sequence and 3D-structure databases. Chapters guide readers through the analysis of 1D protein sequences for coevolutionary fold prediction, protein-nucleic acid interactions, distant homologs and functional motifs, characterization of fold energetics, disordered proteins, mutagenesis-driven modulation of conformational landscapes, 3D protein domains, prediction of 3D protein-protein interactions, and hybrid methods that mine both 1D and 3D genomic and protein databases for gene editing and alternative splicing. Written in the highly successful
Methods in Molecular Biology
series format, the chapters include brief introductions to

the material, lists of necessary materials and reagents, step-by-step, readily

reproducible laboratory protocols, and a Notes section which highlights

tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge,
Protein Evolution: Methods and Protocols
aims to be comprehensive guide for

researchers in the field.

• Reihe: Methods in Molecular Biology
• ISBN: 9781071648278
• Sprache: Englisch
• Erscheinungsdatum: 02.11.2025
• Genre: Technik/Maschinenbau, Fertigungstechnik
• Verlag: Springer US
• Herausgegeben von: Shahid M. Khan, Florencio Pazos