Gapmers

Methods and Protocols

316 Seiten, Hardcover

Kurzbeschreibung des Verlags

This new edition reflects the progression of gapmer research from conceptual foundations to experimental implementation and analytical detection. Beginning with a section covering historical perspectives and the clinical context of antisense gapmers, the book continues with molecular design principles, experimental strategies for developing effective antisense oligonucleotides, methods to evaluate their efficacy and selectivity in cellular and animal models, and analytical approaches for detecting and quantifying antisense oligonucleotides in biological samples. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice needed to ensure success in the lab.

Authoritative and up-to-date, Gapmers: Methods and Protocols, Second Edition serves as a valuable resource for researchers and clinicians aiming to accelerate the development of next-generation antisense therapeutics.

• Reihe: Methods in Molecular Biology
• Themen: Technologie, Ingenieurswissenschaft, Landwirtschaft, Industrieprozesse Maschinenbau und Werkstoffe Materialwissenschaft Technische Anwendung von Biomaterialien
• ISBN: 9781071654750
• Sprache: Englisch
• Erscheinungsdatum: 01.10.2026
• Größe: 25.4 x 17.8 cm
• Verlag: Springer US
• Herausgegeben von: Toshifumi Yokota, Rika Maruyama, Hidenori Moriyama