Cellular Adhesion

Molecular Definition to Therapeutic Potential

350 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

I. Molecular Definition-Adhesion Molecule Structure and Function.- 1 The Biological Function of ?3 Integrins and Other Vitronectin Receptors.- 2 Integrin Modulating Factor and the Regulation of Leukocyte Integrins.- 3 Structure-Function Aspects of Selectin-Carbohydrate Interactions.- 4 Recognition of Cell Surface Carbohydrates by C-Type Animal Lectins.- 5 The Uvomorulin-Catenin Complex: Insights into the Structure and Function of Cadherins.- 6 Cytotactin: A Substrate Adhesion Molecule with Amphitropic Functions in Morphogenesis.- 7 Adhesion Molecules and Bone Remodeling.- II. Biological Consequences of Cellular Adhesion.- 8 Effects of Shear Stress on Leukocyte Adhesion.- 9 Blockade of Leukocyte Adhesion in in Vivo Models of Inflammation.- 10 Proadhesive Cytokine Immobilized on Endothelial Proteoglycan: A New Paradigm for Recruitment of T Cells.- 11 Lung Inflammation and Adhesion Molecules.- 12 Adhesion Molecule-Dependent Cardiovascular Injury.- 13 GPIIb/IIIa Antagonists as Novel Antithrombotic Drugs: Potential Therapeutic Applications.- III. Targeting Adhesion Molecules-Therapeutic Potential.- 14 The Pathological Consequences of Bacterial Adhesion to Medical Devices: A Practical Solution to the Problem of Device-Related Infections.- 15 Peptide Mimetics as Adhesion Molecule Antagonists.- 16 Derivation of Therapeutically Active Humanized and Veneered Anti-CD18 Antibodies.

• Reihe: Springer
• ISBN: 9781461360506
• Sprache: Englisch
• Erscheinungsdatum: 25.09.2012
• Größe: 280 x 210 mm
• Verlag: Springer Nature B.V.
• Herausgegeben von: Brian W. Metcalf, Barbara J. Dalton, George Poste