High-Throughput Metabolomics

Methods and Protocols

459 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about thenext generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

• Reihe: Methods in Molecular Biology
• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Biowissenschaften, allgemein DV-gestützte Biologie/Bioinformatik
• ISBN: 9781493992386
• Sprache: Englisch
• Erscheinungsdatum: 26.09.2020
• Größe: 25.4 x 17.8 cm
• Verlag: Springer US
• Herausgegeben von: Angelo D'Alessandro