Single Domain Antibodies

Methods and Protocols

580 Seiten, Hardcover

Kurzbeschreibung des Verlags

The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications.  In Single Domain Antibodies: Methods and Protocols , expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost.  Written in the highly successful Methods in Molecular Biology ™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

• Reihe: Methods in Molecular Biology
• Themen: Medizin Klinische und Innere Medizin Krankheiten und Störungen Immunologie
• ISBN: 9781617799679
• Sprache: Englisch
• Erscheinungsdatum: 11.08.2012
• Größe: 25.4 x 17.8 cm
• Verlag: Humana Press
• Herausgegeben von: Dirk Saerens, Serge Muyldermans