Sustainability in TIDES Chemistry

Green Approaches to Oligonucleotides and Oligopeptides Synthesis

406 Seiten, Hardcover

Kurzbeschreibung des Verlags

Oligopeptides and oligonucleotides, jointly defined as TIDES, have been neglected in the past as potential drugs due to their short half-life and practical difficulties in the manufacturing processes. The consolidation of iterative synthetic techniques, allowing for design of new chemical entities with better pharmaceutical profiles, has led to renewed interest in these compounds. Large scale manufacturing is therefore now required, and it is important that sustainability and green chemistry are considered from the outset. As the two classes display many similarities, advances in sustainable approaches can easily be adapted from one class to the other. This book brings together all of the information on green synthesis of oligopeptides, which is well established, and all of the preliminary data on green oligonucleotides synthesis, creating a resource that will help chemists to bridge the gap between these two areas.

• Themen: Geowissenschaften, Geographie, Umwelt, Planung Umwelt Nachhaltigkeit
• ISBN: 9781837672585
• Sprache: Englisch
• Erscheinungsdatum: 18.10.2024
• Größe: 163 x 241 mm
• Verlag: Royal Society of Chemistry
• Herausgegeben von: Walter Cabri, Lucia Ferrazzano, Alessandra Tolomelli