2-Oxoglutarate-Dependent Oxygenases

487 Seiten, Hardcover

Kurzbeschreibung des Verlags

Since the discovery of the first examples of 2-oxoglutarate-dependent oxygenase-catalysed reactions in the 1960s, a remarkably broad diversity of alternate reactions and substrates has been revealed. These enzymes are important agrochemical targets and are being pursued as therapeutic targets for a wide range of diseases including cancer and anemia. This book provides a central source of information that summarizes the key features of the essential group of 2-oxoglutarate-dependent dioxygenases and related enzymes for those already working in the field as well as for those newly approaching the topic anew, or interested in translating the basic science into medicinal and agricultural benefits. The book begins with four broad chapters that highlight critical aspects, including an overview of possible catalytic reactions, structures and mechanisms. The following seventeen chapters focus on carefully selected topics, each written by leading experts in the area.

• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Biochemie
• ISBN: 9781849739504
• Sprache: Englisch
• Erscheinungsdatum: 06.05.2015
• Größe: 236 x 163 mm
• Verlag: RSC Publishing
• Herausgegeben von: Christopher J Schofield, Robert Hausinger