Regulatory Peptides and Cognate Receptors

384 Seiten, Hardcover

Kurzbeschreibung des Verlags

In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro". Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a family of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g. CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.

• Reihe: Results and Problems in Cell Differentiation
• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Zoologie und Tierwissenschaften
• ISBN: 9783540653257
• Sprache: Englisch
• Erscheinungsdatum: 18.06.1999
• Größe: 241 x 160 mm
• Verlag: Springer Spektrum
• Herausgegeben von: Dietmar Richter