The Ubiquitin System in Health and Disease

208 Seiten, Hardcover

Kurzbeschreibung des Verlags

Crosstalk Between the SUMO and Ubiquitin Pathways.- A Tale of Two Giant Proteases.- Molecular Genetics of the Ubiquitin-Proteasome System: Lessons from Yeast.- Less Is More: How Protein Degradation Regulates Muscle Development.- Transcriptional Control and the Ubiquitin-Proteasome System.- Ubiquitination of Myc: Proteasomal Degradation and Beyond.- Regulation of Apoptosis and Cytokinesis by the Anti-apoptotic E2/E3 Ubiquitin-Ligase BRUCE.- Dissecting Roles of Ubiquitination in the p53 Pathway.- Regulation of T Cell Differentiation and Allergic Responses by the E3 Ubiquitin Ligase Itch.- Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases.- Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer.

• Reihe: Ernst Schering Foundation Symposium Proceedings
• Themen: Mathematik und Naturwissenschaften Chemie Medizinische Chemie, Pharmazeutische Chemie
• ISBN: 9783540851066
• Sprache: Englisch
• Erscheinungsdatum: 10.12.2008
• Größe: 241 x 160 mm
• Verlag: Springer
• Herausgegeben von: Bernhard Haendler, Stefan Jentsch