CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

344 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

Origin and Generation.- Selection of CD4+CD25+ Regulatory T Cells by Self-Peptides.- The Role of TCR Specificity in Naturally Arising CD25+ CD4+ Regulatory T Cell Biology.- Thymic Commitment of Regulatory T Cells Is a Pathway of TCR-Dependent Selection That Isolates Repertoires Undergoing Positive or Negative Selection.- Selection and Behavior of CD4+ CD25+ T Cells In Vivo: Lessons from T Cell Receptor Transgenic Models.- Migration Rules: Functional Properties of Naive and Effector/Memory-Like Regulatory T Cell Subsets.- Peripheral Generation and Function of CD4+CD25+ Regulatory T Cells.- Dendritic Cells: Key Cells for the Induction of Regulatory T Cells?.- Involvement of Disease Models.- Autoimmune Gastritis Is a Well-Defined Autoimmune Disease Model for the Study of CD4+CD25+ T Cell-Mediated Suppression.- Regulatory T Cells in Experimental Colitis.- Autoimmune Ovarian Disease in Day 3-Thymectomized Mice: The Neonatal Time Window, Antigen Specificity of Disease Suppression, and Genetic Control.- Regulatory T Cells in Transplantation Tolerance.- CD4+CD25+ Regulatory T Cells in Hematopoietic Stem Cell Transplantation.- Naturally Arising CD25+CD4+ Regulatory T Cells in Tumor Immunity.- Phenotypic and Functional Differences Between Human CD4+CD25+ and Type 1 Regulatory T Cells.

• Reihe: Current Topics in Microbiology and Immunology
• Themen: Medizin Klinische und Innere Medizin Krankheiten und Störungen Immunologie
• ISBN: 9783642063763
• Sprache: Englisch
• Erscheinungsdatum: 21.10.2010
• Größe: 235 x 155 mm
• Verlag: Springer
• Herausgegeben von: Elisabeth Suri-Payer, B. Kyewski