Total Synthesis of (±)-Maoecrystal V

von Jianxian Gong

137 Seiten, Hardcover

Kurzbeschreibung des Verlags

In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.

• Reihe: Springer Theses
• Themen: Mathematik und Naturwissenschaften Chemie Organische Chemie
• ISBN: 9783642543036
• Sprache: Englisch
• Erscheinungsdatum: 10.03.2014
• Größe: 23.5 x 15.5 cm
• Verlag: Springer Berlin