Fibrinolytics and Antifibrinolytics

628 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

Section I: Molecular Biology, Biochemistry, Physiology, and Pharmacology of the Plasminogen-Plasmin Enzyme System.- 1 The Fibrinolytic System and Thrombolytic Agents.- 2 Plasminogen and Streptokinase.- 3 Tissue-type Plasminogen Activator (tPA).- 4 Urinary-type Plasminogen Activator (uPA).- 5 The Inhibitors of the Fibrinolytic System.- 6 Assembly of the Plasminogen System on Cell Surfaces.- Section II: Clinical Use of Thrombolytic Agents.- In Acute Myocardial Infarction.- 7 Streptokinase and Anisoylated Lys-Plasminogen Streptokinase Activator Complex.- 8 Tissue-Type Plasminogen Activator (tPA).- 9 Urokinase and Single-Chain Urokinase-Type Plasminogen Activator (Pro-urokinase).- 10 Comparative Evaluations of tPA vs SK with Particular Reference to the GUSTO-I Trial.- 11 Conjunctive Therapy to Reduce the Occurrence of Coronary Reocclusion After Thrombolytic Treatment of AMI.- Thrombolytic Treatment of other Clinical Thromboembolic Conditions.- 12 New Concepts in Thrombolysis of Pulmonary Embolism.- 13 Deep Venous Thrombosis.- 14 Peripheral Arterial Occlusions.- 15 Thrombotic Cerebrovascular Disease.- Thrombolytic Agents in Development, Biochemistry, Pharmacology - Efficacy in Animal Experiments and First Clinical Trials.- 16 Staphylokinase.- 17 Desmodus rotundus (Common Vampire Bat) Salivary Plasminogen Activator.- 18 Thrombus-Targeting of Plasminogen Activators.- 19 The Hunt for the Ideal Thrombolytic Agent: Mutants of tPA and uPA, Chimera of Both Molecules, Fibrolase.- 20 Agents which Increase Synthesis and Release of Tissue-Type Plasminogen Activator.- Autifibrinolytic Agents.- 21 Structure, Pharmacology, and Clinical Use of Antifibrinolytic Agents.

• Reihe: Handbook of Experimental Pharmacology
• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Biochemie
• ISBN: 9783642630293
• Sprache: Englisch
• Erscheinungsdatum: 27.02.2012
• Größe: 235 x 155 mm
• Verlag: Springer
• Herausgegeben von: F. Bachmann