The Ambivalence of Cytostatic Therapy

260 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

I. Tumor Induction by Cytostatics?.- The Carcinogenic Properties of Some of the Principal Drugs Used in Clinical Cancer Chemotherapy.- Experimental Investigations with Anti-Cancer Drugs for Carcinogenicity with Special Reference to Immunedepression.- Tests for Tumor Induction by Antitumor Agents.- Adverse Reactions to Cytostatic Agents.- The Changing Pattern of Hodgkin's Disease Seen at Autopsy.- Tumor Inductions by Cytostatics in Man.- Methodological Problems in the Quantitative Assessment of Carcinogenesis in Long-Term Studies.- Summary.- II Tumor Induction by Immunodeficiency?.- Immune Suppression and Chemical Carcinogenesis.- Experimental Investigations on Immunodepressive Properties of Carcinogenic Substances in Male Sprague-Dawley Rats.- The Significance of Immunosuppression and Antigenic Stimulation in the Development of Malignant Lymphomas.- Malignant Disease in Immunodeficient States in Man.- The Effect of Cytostatic Therapy on Cellular Immunity in vitro.- The Balance of Host Immunocompetence in Chemical Carcinogenesis and "Nonspecific" Immunotherapy.- Tumor Induction in Immunologically Privileged Sites.- Patterns of Neoplastic and Nonneoplastic Diseases of Praomys (Mastomys) Natalensis.- Summary.- III. Cell Synchronization in Tumor Therapy.- The Cell Cycle in Cancer Chemotherapy.- Proliferative Parameters Relevant to Cancer Therapy.- Different Types of DNA-Synthesis and Their Importance in Cancer Growth and Therapy.- Investigations on Partial Synchronization in Ascites Tumors of Different Ploidy and in Solid Transplantable Tumors.- Critical Survey of Experimental Data on in vivo Synchronization by Hydroxyurea.- Cell Synchronization in Solid Tumors.- Experimental and Clinical Results of Chemotherapy after Partial Synchronization of Cell Proliferation.-Problems in the Treatment of Slow-Growing Tumors.- Summary.

• Themen: Medizin Klinische und Innere Medizin Krankheiten und Störungen Onkologie
• ISBN: 9783642809422
• Sprache: Englisch
• Erscheinungsdatum: 16.01.2012
• Größe: 244 x 170 mm
• Verlag: Springer
• Herausgegeben von: R. Gross, Ekkehard Grundmann