Signal Transduction in Cancer Metastasis

300 Seiten, Hardcover

Kurzbeschreibung des Verlags

Overview of Signal Transduction in Tumor Metastasis.- Microenvironment Triggers EMT, Migration and Invasion of Primary Tumor via Multiple Signal Pathways.- The ERK1/2 MAP Kinase Signaling Pathway in Tumor Progression and Metastasis.- Mitogen-Activated Protein Kinase-Activated Protein Kinases and Metastasis.- Grb2 and Other Adaptor Proteins in Tumor Metastasis.- The Role of ROS Signaling in Tumor Progression.- Signal Cross Talks for Sustained MAPK Activation and Cell Migration Mediated by Reactive Oxygen Species: The Involvement in Tumor Progression.- Insights into the Dynamics of Focal Adhesion Protein Trafficking in Invasive Cancer Cells and Clinical Implications.- Notch Signaling in Cancer Metastasis.- New Concepts on the Critical Functions of Cancer- and Metastasis-Initiating Cells in Treatment Resistance and Disease Relapse: Molecular Mechanisms, Signaling Transduction Elements and Novel Targeting Therapies.- Involvement of Lipid Rafts in Growth Factor Receptors-Mediated Signaling for Cancer Metastasis.- Cadherin-Catenin Signaling in Ovarian Cancer Progression.- PTP4A3, a Signal Molecule Deregulated in Uveal Melanoma Metastasis.- Signal Transduction Pathways Involved in Hepatocarcinogenesis and Metastasis of Hepatoma.

• Reihe: Cancer Metastasis - Biology and Treatment
• Themen: Medizin Klinische und Innere Medizin Krankheiten und Störungen Onkologie
• ISBN: 9789048195213
• Sprache: Englisch
• Erscheinungsdatum: 04.10.2010
• Größe: 241 x 160 mm
• Verlag: Springer
• Herausgegeben von: Chi-Tan Hu, Wen-Sheng Wu