Mathematical Models for Therapeutic Approaches to Control Psoriasis

von Priti Kumar Roy, Abhirup Datta

89 Seiten, Taschenbuch

Kurzbeschreibung des Verlags

This book discusses several mathematical models highlighting the disease dynamics of psoriasis and its control. It explains the control of keratinocyte concentration through a negative feedback mechanism and the effect of including a realistic time delay in that system. The effect of cytokine release is described in a mathematical model of psoriasis and further elucidated in two different mathematical pathways: the ordinary differential equation model system, and the fractional-order differential equation model system. The book also identifies the role of CD8+ T-cells in psoriasis by investigating the interaction between dendritic cells and CD8+ T-cells. Presenting an approach to control the fractional-order system to prevent excess production of keratinocyte cell population, the book is intended for researchers and scientists in the field of applied mathematics, health informatics, applied statistics and qualitative public health, as well as bio-mathematicians interested in the mathematical modeling of autoimmune diseases like psoriasis.

• Reihe: SpringerBriefs in Applied Sciences and Technology
• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Biowissenschaften, allgemein DV-gestützte Biologie/Bioinformatik
• ISBN: 9789811390197
• Sprache: Englisch
• Erscheinungsdatum: 30.07.2019
• Größe: 23.5 x 15.5 cm
• Verlag: Springer Singapore