Nucleic Acid Therapeutics

Volume II: Research and Development

499 Seiten, Hardcover

Kurzbeschreibung des Verlags

This book provides a systematic and interdisciplinary introduction to nucleic acid therapeutics (NATs)—a rapidly advancing class of biopharmaceuticals based on engineered DNA and RNA molecules. It features clinically validated and experimental technologies such as siRNA, mRNA, CRISPR, and RNA circuits, and offers insight into multitarget NAT design guided by polypharmacology principles. Special emphasis is placed on chemical modification, delivery systems, regulatory pathways, and synthetic biology tools. Readers will benefit from practical guidance, translational relevance, and conceptual clarity that bridge molecular mechanisms and therapeutic applications. The book is intended for researchers, clinicians, students, and professionals seeking to advance innovation in genomics-driven drug development and modern precision medicine.

This volume II focuses on the translational and developmental aspects of nucleic acid drugs, including chemical modifications, GMP-compliant manufacturing, and delivery technologies.

• Themen: Mathematik und Naturwissenschaften Biologie, Biowissenschaften Molekularbiologie
• ISBN: 9789819246335
• Sprache: Englisch
• Erscheinungsdatum: 28.10.2026
• Größe: 23.5 x 15.5 cm
• Verlag: Springer Singapore
• Herausgegeben von: Zhiguo Wang, Xiaofang Zhang, Jinghao Wang